Hemangioma (ICD-11: 2F25 / ICD-10: D18) 💚

Hemangioma – (angioma, vascular nevus) benign neoplasm formed by local accumulation and proliferation of small blood vessels (capillaries) on the skin. It is represented by a flat or slightly elevated formation of bright red color of various sizes and shapes. Hemangioma can be either congenital or acquired (appear throughout life). The multiplicity of the lesion is especially characteristic of small acquired hemangiomas, but there are also congenital multiple forms (hemangiomatosis). Equally common in males and females (congenital – more often in females).

Predisposing factors

There is no clear reason for the appearance of hemangiomas. It is only appropriate to talk about predisposing factors that, to varying degrees, can increase the risk of neoplasms.

For congenital hemangiomas:

1. Female gender of the child;
2. Prematurity;
3. Maternal viral infections and various intoxications during pregnancy;
4. Mother’s age is over 40;
5. Intrauterine hypoxia;
6. Multiple pregnancies;
7. Genetic factor.

For acquired hemangiomas:

1. Pathology of the vascular wall;
2. Impaired liver function;
3. Endocrine pathology;
4. Metabolic disorders in the body;
5. Exposure to the skin of ultraviolet and ionizing radiation;
6. Environmental factor;
7. Genetic factor.

Diagnostics

Diagnosis of hemangiomas is based on a clinical examination, which includes a routine examination of the formation and dermatoscopy. If you suspect malignant growth, a biopsy can be performed.

In the diagnosis of congenital hemangiomas, which can be deep, occupy a large area, located in the area of ​​vital organs and vascular structures, be part of congenital syndromes (for example: Sturge-Weber syndrome), an ultrasound diagnosis and a comprehensive examination by several related specialists are performed.

Symptoms

A visual examination of hemangiomas can have significant differences.

Congenital hemangiomas come in various shapes (oval, asymmetric, occupying a large area, and several anatomical areas). The surface is not changed (normal skin pattern), which is typical for flat, not protruding hemangiomas, smooth (smooth skin pattern), or slightly bumpy (typical for gross hemangiomas rising above the skin).

The boundaries of hemangiomas are clear, but often uneven (especially with large sizes, small with even contours). The color is represented by various shades of red (pink, bright red, raspberry, crimson, cyanotic), most often uniform throughout the area, but sometimes there are “spotting” or variegation. As a rule, it does not affect hair growth.

The size of congenital hemangiomas can vary within wide limits: from point formations (2-3 mm) to large, occupying several anatomical areas (20-30 cm). On palpation, the hemangioma is soft, somewhat softer than the surrounding skin, the structure is more delicate. When pressed, it may fade. There are no subjective sensations. Hemangiomas are located mainly on the head (face, scalp), neck. Less commonly, other anatomical areas.

Acquired hemangiomas usually have the appearance of a hemispherical (rarely on a wide stalk), symmetrical (oval or round) nodule that rises above the skin. The surface is slightly different from the texture of ordinary leather, but can be smoothed or even glossy.

The boundaries are clear and even. The color is uniform, bright red, less often – other shades of red. It does not affect hair growth.

Dimensions are usually small, up to 5-7 mm. Sometimes there are hemangional papillomas protruding above the skin, the height of which corresponds to the width. On palpation, the hemangioma is soft, from pressure, it turns pale. There are no subjective sensations. They are located mainly on the trunk and upper limbs, but can also be found on other parts of the body.

Dermatoscopic Description

With dermatoscopy, the following hemangioma features are visualized:

• Symptoms of rigidity and filling – a sign of the elasticity of the tumor, which, when compressed, pales and decreases in size;
• After weakening the pressure, the formation acquires the former color and shape;
• A large number of small vascular (red) gaps, separated by thin blue jumpers;
• The presence of large blue-violet gaps is a sign of deep-lying venous hemangiomas;
• Blue-black and black-red lacunae with a yellow rim on the periphery are a sign of injured hemangioma with subsequent thrombosis of vascular lacunae.

Differential diagnosis

Differential diagnosis is carried out with such neoplasms as:

• Various types of hemangiomas (congenital, acquired, as part of the syndromes, deep, superficial, etc.)
• Pyogenic granuloma;
• Blue nevus (deep, venous hemangiomas);
• Angiosarcoma;
• Kaposi’s Sarcoma;
• Mushroom mycosis (T-cell lymphoma of the skin).

Risks

Hemangioma is safe and does not carry an increased risk of a malignant tumor. In the absence of external influences (trauma and other damaging factors) – the risk of malignant degeneration is comparable to the same risk on unchanged skin.

Signs of a possible malignancy: a change in appearance, the appearance of subjective sensations.

In addition to oncological risk, hemangioma (especially large sizes) can lead to rather massive bleeding if it is damaged. Also, large hemangiomas can ulcerate with the addition of an infection (with chronic injury, damage).

Tactics

The tactics of managing hemangiomas depends on various factors.

The decision on large congenital hemangiomas, as a rule, is made with the participation of doctors from various specialties: pediatricians, dermatologists, oncologists, surgeons, and others, if necessary. Indications for treatment and the timing of interventions are set individually depending on the effect of hemangiomas on the vital functions of the body. The issue of treatment priority in identifying other concomitant pathologies and disorders in the body is also important. When choosing tactics for dynamic observation (possibly with small superficial hemangiomas located on the trunk, limbs, in the absence of complications and rapid tumor growth), individual recommendations are formed.

In the case of acquired small hemangiomas, in the absence of any damaging effects or changes in appearance and subjective sensations, removal is not necessary, self-monitoring (or examination with the help of other persons in inaccessible areas) is sufficient at least once a year. If mechanical damage to the hemangioma has occurred, changes in appearance have been noticed, or previously absent sensations have appeared, consultation with a dermatologist or oncologist is necessary.

The specialist determines the possibility of further dynamic monitoring (terms are determined individually) or indications for removal are set. It is necessary to remove those hemangiomas that are subject to constant, chronic trauma to clothing, jewelry, or due to the nature of professional employment.

In the case of dynamic observation, photo fixation of skin neoplasms is of great value, which will subsequently determine even minor changes in appearance.

Patients, in the presence of other skin neoplasms (nevi) in combination with hemangiomas, are shown an examination by a dermatologist or oncologist in the spring and autumn (before and after the beach season). Such patients are recommended to compile a map of skin neoplasms, which greatly simplifies further observation, the search for new formations, or a change in existing ones.

Treatment

Less traumatic methods can be used to treat hemangiomas:

• Laser treatment: the safest and most effective method, used for hemangiomas of various shapes, sizes and localization;
• Cryodestruction with liquid nitrogen: applicable for small superficial hemangiomas, the method is associated with a high risk of scarring;
• Subclinical hardening: applicable for small, delimited hemangiomas.

If it is impossible to conduct less traumatic treatment, as well as in the event of life-threatening conditions (for example, bleeding), surgical removal of hemangiomas is used.

Due to the high risk of recurrence of hemangiomas (especially congenital), repeated courses of treatment or operations are often required.

For the treatment of congenital hemangiomas, in combination with the methods listed above, drug therapy is also used: beta-blockers (propranolol, atenolol, timolol (externally)), steroid hormones (prednisolone), antitumor drugs (vincristine).

Prevention

Prevention of congenital hemangiomas is reduced to the proper management of pregnancy, minimizing stress and eliminating the use of drugs not recommended during pregnancy, to avoiding and timely treating infectious diseases, and eliminating smoking and alcohol consumption.

Prevention of the appearance of hemangiomas and their malignancy consists in a gentle and careful attitude to the skin:

• Exclusion of chronic skin trauma;
• Observance of safety measures during the work with the skin-damaging factors;
• Timely treatment of concomitant pathologies;
• Personal hygiene and basic awareness regarding skin neoplasms.

It also requires regular examination of all hemangiomas on the skin, timely consultation with a specialist in the event of external changes, and the removal of potentially dangerous neoplasms.